SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '064c2b2c8cf515fdad44fc8cc3b309ab1fc007d018eda8b553f533506db2c920' 
  AND token = 'EzXCMMWx3xqh8xSCRKs2zrhbTp93EaaaUTUDNqEEfSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}