SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5dad1e5a53832d9cbf887eb4a294b6f8b37b2705097b25a686187f04724857' 
  AND token = 'kREJSYb4BFXPY4oq3W8f3r95hd4Xj8DybtiTE3ppQwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}