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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a6771a97e4381bd78a89fed301791ad4bad3f434b9da7ef0be86364da91efd0' 
  AND token = 'RD4r6QTNNavbhAKObXFIhmEFmNLsAn3c0kXxHZ82vaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}