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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d2aa8d2773bfa160dbf2d15b6183873a76e711edcabf75e2f309f0b83119d3' 
  AND token = 'MnC/9Lw7RzO4B6VxmeFpdffC1k0s0eSeNxu8ynNAEDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}