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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f3a9a2efd1a403d4d37d7ea3a180390fe8a7841f09cd75d0c04002b30c2eff' 
  AND token = 'jkTOhcZkLcagfGwMyMT7vFnWH+HWW/4Ds2OhsZDlUN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}