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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e35014484a1bc2a04435cfa7f618416e83159726a54887d9e1c3e9926fc2d72' 
  AND token = 'XNbB0JYnZ9Epe2xd7lPD/3MYdMqqnic5XpoxQLFPn/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}