SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880791ec6bef9be7d3b72428172ee8368d7435bab5ebaec2afd6d3bce1e35e5c' 
  AND token = 'GQQxgvwq7O56UNE+E3GRe262tPNlSKP1495NMsMP2cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}