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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c04824cf8f105a1719329dde67d114a7a515e12447c32c8f83fcff85dd440205' 
  AND token = '2oYAAmFj1dwWO2b0Bq7PZ5AXpSPy/r2uQT6nxHwy9zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}