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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3192d3edc04388f00b63e06eaedc3ea2b3dcb7a0f0405312bf1acca8c0c78f4' 
  AND token = 'Vwlp45BhGr/BEYMCi0g33/v7PCMNO5RVXTcRrbGuY/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}