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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ec7f211e5a4bba0016406b00ce89e078103de4a38f9a8e88a9c4769c222931' 
  AND token = 'HOp0JWbY+FnCZHUCUKa7f/dBca+E06JLXG/C18wrjmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}