SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b225485b02581bb25db06d1b3dd3275bb9dc3a811777be8168fb58f362683fe' 
  AND token = '1/O1ebsKwho88qeMC8vhQsa/ctDQ9dDuZFsMQrUsYe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}