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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '675f91eab340f601c95156c3bd3f13f65082cf1b5edacf3384ece8c1115f0073' 
  AND token = 'llZchG8Bo2wIecRToT3QcbAHatmesq2x0zt0mL60fPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}