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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef12275d760d0f71ff34ac92aca67ff32493eff3dd8f60e1c06c83c455e5e600' 
  AND token = '0QCHSx/Zqt5ysB0b8hkFEj8Z+FAmrM/acghTz5Vaem4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}