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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3b0cd321b7c68ca77376b76a47ed408f635be9466a322b8ec839de232d47d0' 
  AND token = 'AFKIgpe+F7dy9V4d8rJYEUVU1NxO01Ln7W5oVLbHHnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}