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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7246e8ed73813be41ac6635e79cb41b05c8b4e7872b8d16c4fb4290281a15fe' 
  AND token = 'DyP6ZCmTHvxCY/vl/3HC830LNYfdzunWdrrAC+d0LgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}