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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4acec656bede54abfea8aa4ed0316c02a7dab690b67ea9f892e59aade0c21aea' 
  AND token = 'Xm8Klya3wZVYN4As1bBJjc881WP3tu8XZRY3nK9UZFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}