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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b649240caaa1e0e6dfb176ee73c49a4be33e2e70412cfccc41108ac77c8b97b6' 
  AND token = 'LdMEStz4dv9z0PbD650oZh3QM3IzDIDoMn6fjWKBN3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}