SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '524f59e6865508265adf02edeaa0c5562583bcf5c9fbdc14c6735397e96267a3' 
  AND token = '3SUH+qL4uubvrR+euhshfolCjnWTbnWUG8P8fOpwkos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}