SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c81002fc99fd53183ccba76ebf7fe9b1f122d59d8270e261f7b408387fb6a88' 
  AND token = 'pwdijBYDtX0aRKpc0/y5rfpu3bQzBtMCE3y3kL76Z34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}