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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ec1de7b01ec078864c34b4eb96ea8c86c099a7709b9d1952de0947fd2ef534' 
  AND token = 'MQvtr97SHSKgMT5t+0tHuBnNOCIZ0zeDq7vldL8vj8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}