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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e834ddc2fe96899fd49659555c4322d290327cbf49cc251d63d8be56e852219' 
  AND token = 'fBMotQqYZ6cI2NFmqsPUri9wh9BFnbwdBTUbP02WWS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}