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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290b5bb14b26424d6c70862d8eb25a89026a651e9ae7e5e219db27df0c40bbf3' 
  AND token = 'v1fLQztYMPIes2bVBlbAqo1caJTg5+S38b+UBmugFNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}