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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e64b9273849e1ae828c076a203e7c22b07ff5c11793db06e9c8a126a6f4ccf3' 
  AND token = '+OoxNL1mUxufaiSbDWD6syKU1kOk4b/8poRd9wGuvM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}