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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6647b2724f9156014c67508513a7e48db62efc2bec5f528dae1ea46f74d525' 
  AND token = 'MOYJgjOECjE6rzqEq16O8baliwzZFPD5SM0vJMYlWpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}