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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c9b7b90549b9bfb328c0e65fff516c581aa57719581243c77b2d3c1dd15bb3' 
  AND token = '4lR1VtnZ3K01dv9e4Omzoc8uRFYpyg8uhfRS1LSj9wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}