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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe2170d191c2162851d0f80e5274a9d9c9e110b41ae6da002cb9e262abb7f37' 
  AND token = 'RNxYiKE6/F/3Nd7hYoK36tObrSM6WlrC3tOrgho0EnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}