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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81353a8c9add26ab0532424d2f8d33a38ca5e43e6d8d0061e44b3cfdae30434a' 
  AND token = 'T3tfpyDDAAXwk9LM9rq4YvKmTMIMrxFjlzhzuEQSeNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}