SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8570bfeb095bec26ebeff265715159527582357e1f7daf3872451341af1cc003' 
  AND token = '4Z2Aq5+VQmubWH4+sEvYQCEPgkb+9w/TwNpQVZ32rv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}