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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd610e0c2d1d85bd49b11e230dddec0da5c44c8fea345ae1d486078a0407979f2' 
  AND token = 'iZ0o8o1w2TaM0hxokJg2FgBS7/rt5BCteFPfxuJmLqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}