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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df2fc4746ab99af4ed5585bbc3e00aebc1392f2592df12c5684cec0c1f91140' 
  AND token = 'McV0h2wo7hjt1xQ+vujwiBrCaTrRd+Clbd91eV2m7U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}