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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dba9741b049f72d4be81a3552a0ddb957f9f5ecbf539470d54e0a339eef04167' 
  AND token = 'jRET0qbdyrkdW0kJ/7FmlRvIhgcvjLwOk1Yq2QeyWkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}