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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '795bf037d53733e78f3f30d8fc791a16838f191a46fbb443e27abade59e432f7' 
  AND token = 'ks27yls0oGJM2xHav6tZM/9Adno0gaaAgdS/iXHGZI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}