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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5b5fb9fdb64c3948259351020671d19cb0695d271a29cf02c00dc442354da7' 
  AND token = 'J3IGIAygySW/ZrcZg9cbAA5vP5I0aOs8ZsQS3GXjZ+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}