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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed850b0a6dcb8d9323ca5a90dd8610b74d5f319bbe0332700da99d25f8343a7f' 
  AND token = 'bI0nMD6DISQPK4oFysLFdQ6q0Fe3zpuIeGaET7LayUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}