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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a22a2a337a3353381c101ce4fc379a42ca3fa563d5f20d7df9873279da93b5' 
  AND token = '+OWqIbhuvBtt5V9uQJrd9U2bDwyRF3UXqQ8CchuU/W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}