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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8bdd4723cc3518f85fc43999e90204be030d99ef2e7a64050332ddfae2338dd' 
  AND token = 'S+ech4OCGVf9zqO+x0suxowWVcsWXaJCrveNNpEoAKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}