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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adb2cbd52540115d9f62cc88b462da693bf57d2f153cec0f4309ddd6274c6a9' 
  AND token = 'l0Eg0py+0e3ioyCvXiCrSgz+HgK4S9zgPgxDdiy5HiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}