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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26760b447fbf27033237f6889cea3259cae88b5aa532abf20f6a91ce074c58c4' 
  AND token = '+pst11TCLR8SRaBebUQm5o6gKT5RFFvCRUXPII9uvrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}