SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0da4ee1d01a3c21b74d61d3177c56ea652bc5e00005c4efdb182b6c5381c26' 
  AND token = '5pDu2vMg9OnVbmiwSeT4ivQ86nDd2s8ZpsTODyJoKtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}