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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cc549489e8e45bd9ce73fee1cffc5cdc28a609e22fa89e1dc769e55d5d15212' 
  AND token = '27RCCVZ6u2dK8rv0xZ2sGhbIwOqjbBj8wnOqL0ADEpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}