SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6ca30b1812b5729b684bbf3d9663b8077cdb73fb8c45eaf2e17ea16e273f39' 
  AND token = 'LCtogy/aytjct9WjtRiu2egQn9MVN47yOKxevBl98Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}