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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561a229395d81f1fe842aa4a0d98f302e88b6c58804982367986bf4e3dd1aa8d' 
  AND token = 'xw2fI66vcXHGNSACXXYqirtaHMPQMh4DNoDvQbgF/9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}