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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c1d488475e4fb875cd8627e8836f48b8b8ec58691f6a4993f6552a6e787245' 
  AND token = 'J64a7fxfYI4jEryldrWhjyhltIyJmhobM9LXtDJZucE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}