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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6037e50097dc8311507ec1483a05ddf22be63ec376f2cc3de56f0e5ca62ff2' 
  AND token = 'V8Z0TJzybCSL7dv4zna+dCA/4j4ZV8LEWFK013kOjW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}