SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e2664ce33d582e1df2a85c69db5c6a85dee6435fe30b1ae4636588f9d6ac9a2' 
  AND token = 'wKJpJ5ufhrFHkG8zoVF8kqdGeAD1erxyxE4jcFxwEZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}