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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e37f34706727d4bebf50f9f91b5c926fd55b9cc585840d561995791f01ca22' 
  AND token = 'JRyH/fc58O684R+5IV/3hMhgL8FGSm0UH/UsE0/fzYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}