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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f32c330b2c77e2940389e9a7d696a612d88aeeed7dc2fc14a741add673045c08' 
  AND token = 'qTEiD7Dt8/mx0cvEEiDCClqoNPU4blCSeLbiupVUoEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}