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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2375dbad76ea058c985132350dfb1be8884790be9266c89798a57c12fa9fd47d' 
  AND token = 'HdHuSAlWRUZoNpxtlE4/QqX+Esk6EHN0XRQcxah83xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}