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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede83688f89b086585d0c5e46fb3c90b41bfed682b4086b9aeb59bdd7e55e91c' 
  AND token = 'G5H4bcjanORnXTiRuAQc5LCmDa2p8S4vmkQ5bfCB5vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}