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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b9c3288a369962d3ebc1e11dfdbdeb22a7208c4d061db1dbc18777de4d582d' 
  AND token = 'ODtu68Z5+H80KtUywM7AEHGiIbc7U4j6jn9lVNZupVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}